RiPPMiner | A Bioinformatics Resource for Deciphering Chemical Structures of RiPPs

Name

Mersacidin

Class

lanthipeptideB

Modification System

LanM

Producer Organism

Bacillus sp (strainHIL-Y85/54728)

Uniprot ID

Sequence

MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGAGDMEAACTFTLPGGGGVCTLTSECIC

Leader peptide

MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGAGDMEAA

Core Peptide

CTFTLPGGGGVCTLTSECIC

Modified Residues

16	2,3-didehydroalanine (Ser)

Cross-links

1--2	Beta-methyllanthionine (Cys-Thr)
4--12	Beta-methyllanthionine (Thr-Cys)
13--18	Beta-methyllanthionine (Thr-Cys)
15--20	S-(2-aminovinyl)-3-methyl-D-cysteine (Thr-Cys)

PDB ID

CLUSTER ID

Literature REF

CLUSTER

Gene Name	Gene Description	Protein ID	Domain Analysis	Uniprot/PDB
mrsK2	MrsK2 protein putative histidine-kinase			GOA Uniprot
mrsR2	MrsR2 protein putative response-regulator			GOA Uniprot
mrsF	MrsF protein putative ABC-transporter			GOA Uniprot
mrsG	MrsG protein putative ABC-transporter integral membrane			GOA Uniprot
mrsE	MrsE protein putative ABC-transporter integral membrane			GOA Uniprot
mrsA	MrsA protein mersacidin pre-peptide			PDB GOA Uniprot
mrsR1	MrsR1 protein putative response-regulator			GOA Uniprot
mrsD	MrsD protein putative mersacidin modifying enzyme			PDB GOA Uniprot
mrsM	MrsM protein putative mersacidin modifying enzyme			GOA Uniprot
mrsT	MrsT protein putative ABC-transporter			GOA Uniprot