RiPPMiner | A Bioinformatics Resource for Deciphering Chemical Structures of RiPPs

Name

Ruminococcin A

Class

lanthipeptideB

Modification System

LanM

Producer Organism

Ruminococcus gnavus

Uniprot ID

Sequence

MRNDVLTLTNPMEENELEQILGGGNGVLKTISHECNMNTWQFLFTCC

Leader peptide

MRNDVLTLTNPMEENELEQILGG

Core Peptide

GNGVLKTISHECNMNTWQFLFTCC

Modified Residues

16	2,3-didehydrobutyrine

Cross-links

7--12	Beta-methyllanthionine (Thr-Cys)
9--23	Lanthionine (Ser-Cys)
22--24	Beta-methyllanthionine (Thr-Cys)

PDB ID

CLUSTER ID

Literature REF

CLUSTER

Gene Name	Gene Description	Protein ID	Domain Analysis	Uniprot/PDB
	hypothetical protein			GOA Uniprot
rumR2	RumR2 protein putative response-regulator			GOA Uniprot
rumH	RumH protein putative ABC-transporter integral membrane			GOA Uniprot
rumG	RumG protein putative ABC-transporter integral membrane			GOA Uniprot
rumE	RumE protein putative ABC-transporter integral membrane			GOA Uniprot
rumF	RumF protein putative ABC-transporter (ATP-binding domain)			GOA Uniprot
rumR	RumR protein putative response-regulator			GOA Uniprot
rumK	RumK protein putative histidine-kinase			GOA Uniprot
rumA1	pre-RumA ruminococcin A pre-lantibiotic			GOA Uniprot
rumA2	pre-RumA ruminococcin A pre-lantibiotic			GOA Uniprot
rumA3	pre-RumA ruminococcin A pre-lantibiotic			GOA Uniprot
rumM	RumM protein putative ruminococcin A modifying enzyme			GOA Uniprot
rumT	RumT protein putative ABC-transporter			GOA Uniprot
	hypothetical protein			GOA Uniprot